How to complete Unblinding

Step 1. Follow the unblinding link above or below to access treatment information in an emergency.

Step 2. You will need to enter your GMC number and NHS email address

Step 3. Enter the participant’s ID number and date of birth. The participant’s ID number can be found on their EJS ACT-PD participation card.

Step 4. Unblinding and allocation details will be sent to the NHS email address provided.

Contact Details

If you have any questions, please refer to the participant's card for local site contact details or out of hours numbers.

To contact the EJS ACT-PD team:

Phone UCLH out of hours emergency number 020 3456 7890 and ask for Prof Tom Foltynie.
Phone Newcastle Hospitals NHS Foundation Trust out of hours emergency number 0191 233 6161 and ask for Prof. Camille Carroll.
Email: mrcctu.ejsactpd@ucl.ac.uk (working hours only)

Unblinding and Pregnancy

Any pregnant participant must stop trial treatment in the event of pregnancy. Unblinding procedures should be initiated as it may implicate how pregnancy is managed. Unless the participant wishes to terminate the pregnancy for other reasons

Unblinding in the case of pregnancy can be completed by the PI but must not be completed by the blinded rater.

Unblind a Participant

Click the Unblind button to unblind a participant.

Please see advice on this page.

Unblinding should only be performed by an NHS doctor and should only be considered where knowledge of treatment allocation is essential to guide clinical management.

EJS ACT-PD is a double-blind trial. This means that neither the participant nor their doctors or study team know which treatments they have received.

Participants in EJS ACT-PD trial could be taking:

Telmisartan – up to 40mg a day

Terazosin – up to 5mg a day

Placebo

Unblinding of allocation to trial treatment can be performed if required only in a medical emergency, where knowledge of the participant’s treatment allocation would change immediate clinical management. This can be requested by any treating doctor and performed in medical emergencies.

The doctor requiring the unblinding may contact or notify the participant’s site prior to unblinding to discuss the circumstances if this will not result in a delay to treatment; site contact details (including out-of-hours contact) can be found on the participant’s card.

If it has not been possible to contact the participant’s local site, the trial emergency numbers (also found on the participant's card and on this webpage) can be used to contact the delegated members of the EJS ACT-PD Trial.

However, if it is not possible to contact a member of the trial team via the trial emergency number, the procedure for rapid break of blinding is in place so that unblinding can be performed to not delay treatment.